Job Description

Core responsibilities:

• Run routine radioligand binding assay protocols, analyze data & generate weekly reports, carry out tissue culture and cell-based binding assays.

• Fully document all experiments in our electronic laboratory notebook.

Quals--

Qualifications

Education: B.Sc. with 6+ years or M.Sc. with 4+ year or PHD with 3+ years of laboratory experience practicing the required skills.

Must Haves/Required skills:

• Prior experience developing equilibrium and kinetic radioligand binding assays (e.g. 125I, 3H, 35S) in relevant formats is preferred, or willingness to do radioligand work.

• Tissue culture including: (i) cell plating, (ii) cell stimulation and (iii) cell harvesting.

• Experience in membrane preparation

• Experience working with multiwell plates (96- and 384-well formats)

• Note that this position is laboratory-based.

Nice to haves/Preferred skills:

• Experience with liquid handling automation systems (e.g. Echo, Bravo).

• Familiarity with multi-mode plate readers such as the SpectraMax and EnVision Multilabel Reader.

• Exporting and dose-response fitting of data from binding assays.

• Running research operating plan assay and data upload (ROP assay, ActivityBase application)

• Experience with traditional Western blot techniques, including requisite data analysis used to determine abundance of given protein targets. Knowledge of the Protein Simple high-throughput, automated western blotting system is preferred but not required.

Computer/Software skills:

• MS Office suite, Adobe PDF –must have

• Prior experience with an electronic laboratory notebook system is desirable but not required.

• Prior experience with data analysis packages including GraphPad Prism, Activity Base, etc. is desirable but not required.

Personality:

Team oriented, detail oriented, highly collaborative, joyful, and understands timelines.

Note:

• This position is laboratory-based, onsite role.

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